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发布于:2019-12-10 09:31:18  访问:26 次 回复:0 篇
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Vity aspect DNA restore helicase DNA maintenance helicase Uncharacterized 1 3 four 3 three 3 4 3 Amenable Amenable
aeruginosa P. aeruginosa P. aeruginosa Quinolone signal PS-341 manufacturer response protein Possible FAD-dependent monooxygenase Uncharacterized Nucleoside-diphosphate-sugar PRN1371 SDS epimerase Probable aminotransferase Uncharacterized 3-Oxoacyl-[acyl-carrier-protein] synthase III four one one four 3 4 two four three 4 3 four Highscoring Highscoring Highscoring A A A 2VW8 2X3N 2X5E 2X4G 2X5D 2X3O 2X3E 3FFE [45] 2X0O 2X4L 2X5P 2X5F ClusterRecalcitrant ?Amenable BRecalcitrant ?Recalcitrant A Highscoring Highscoring Highscoring A A APectobacterium chrysanthemi Achromobactin synthetase Bordetella bronchiseptica Streptomyces coelicolor Streptococcus pyogenes Methicillin-resistant Staphylococcus aureus (MRSA) MRSA Alcaligin biosynthesis protein C Putative Procyanidin B1 custom synthesis ferric-siderophore receptor protein Fibronectin binding protein Asp/Tyr/Phe pyridoxal-50 phosphate-dependent aminotransferase Pantothenate synthetase Mevalonate kinase Orn/Lys/Arg decarboxylase spouse and children protein Putative 4-oxalocrotonate tautomerase Putative phosphofructokinaseRecalcitrant A HighA scoring Highscoring Amenable Highscoring Amenable Amenable Highscoring Amenable A A A ?A A AMR1 1 two 52X3F 2X7I 2X3L 2X4K 2JG5 2JG6 2JG2 [56] 2W82 [57] 2WJ9 2V1L [58]Sm Pt MRSA Se-SAD Zn MR MRSA MRSA MRSAZn-SAD MRSA MR Pt Pt MIRAS Sphingomonas paucimobilis Transposon Tn916 Escherichia coli Vibrio choleraeDNA-3-methyladenine glycosylase I one Serine palmitoyl transferase Procyanidin B1 Autophagy Antirestriction protein Antirestriction protein Hypothetical protein 2 three 4Recalcitrant ?Recalcitrant A Highscoring ARecalcitrant AThe Scottish Structural Proteomics Facility Desk 3 continued Constructions Phasing strategy Origin Function/commentsRetrospective evaluation of target PDB code choice [reference] XtalPred ParCrys Cluster 2X7B 2X4I Sm-2X5G; Dm-2X5H 2X48 2X3G 2X5C 2X4J 2VXZ 2X3M 2X5R 2VH3 [54] 2VHS [59]Ard1 SIRV-ORF114 (CAG38848) SIRV-ORF131 (CAG38830) SIRV-ORF55 (CAG38821) SIRV-ORF119 (CAG38829) PSV-ORF131 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/21311040 PSV-ORF137 PSV-ORF165a PSV-ORF239 PSV-ORF126 Eukaryotes Ranasmurfin Cathepsin-L mutant MR Se-SADS. solfataricus Sulfolobus islandicus rudivirus (SIRV) SIRVN-terminal acetylase Uncharacterized Uncharacterized Uncharacterized Uncharacterized Uncharacterized Uncharacterized Uncharacterized Uncharacterized Uncharacterized Uncharacterized Silica polymerization3 two 4 5 5 4 3 4 five 3 4Recalcitrant ?Highscoring AArchaea viruses and bacteriophagesRecalcitrant ?Recalcitrant ?Recalcitrant ?Recalcitrant ?Recalcitrant ?Recalcitrant ?HighA scoring Recalcitrant B Amenable Amenable A AZn-SAD SIRV Se-SAD S-SAD Se-SAD Se-SAD SIRV Pyrobaculum spherical virus (PSV) PSV PSVSulphur- PSV Unfortunate Zn-SAD PSV Zn-SAD Polypedates leucomystax MR HumanThe PDB code for every framework is indicatedand 11 proteins by ParCrys vs . pI/GRAVY plot. This discrepancy may possibly be because of to diverse parameters used with the predictors particularly; dimension, homologs in PDB, GRAVY index and pI. Therefore, it truly is fair to recommend that at the very least two predictors should be utilized to be able to supply a broader protection of crystallization room. Scientific highlights Reviews describing the crystal buildings and biochemical analyses of ten SPoRT-generated targets have been revealed in peer-reviewed journals (see Tabl.Vity factor DNA mend helicase DNA repair service helicase Uncharacterized one 3 four three 3 3 4 three Amenable Amenable Amenable Amenable Amenable Amenable Amenable ???A ???2X5Q 2X4H 2W0M [50] 2X3D 2IX2 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/20954872 [51] 2VL7 [48] 2VA8 [49] 2IVY MR Sm MR Direct MR Se-SAD MR Se-SAD SIRAS Br Pt MR Pseudomonas aeruginosa P. aeruginosa P. aeruginosa P. aeruginosa P. aeruginosa P. aeruginosa P. aeruginosa Quinolone sign reaction protein Probable FAD-dependent monooxygenase Uncharacterized Nucleoside-diphosphate-sugar epimerase Possible aminotransferase Uncharacterized 3-Oxoacyl-[acyl-carrier-protein] synthase III four 1 one 4 3 4 two 4 three four 3 4 Highscoring Highscoring Highscoring A A A 2VW8 2X3N 2X5E 2X4G 2X5D 2X3O 2X3E 3FFE [45] 2X0O 2X4L 2X5P 2X5F ClusterRecalcitrant ?Amenable BRecalcitrant ?Recalcitrant A Highscoring Highscoring Highscoring A A APectobacterium chrysanthemi Achromobactin synthetase Bordetella bronchiseptica Streptomyces coelicolor Streptococcus pyogenes Methicillin-resistant Staphylococcus aureus (MRSA) MRSA Alcaligin biosynthesis protein C Putative ferric-siderophore receptor protein Fibronectin binding protein Asp/Tyr/Phe pyridoxal-50 phosphate-dependent aminotransferase Pantothenate synthetase Mevalonate kinase Orn/Lys/Arg decarboxylase household protein Putative 4-oxalocrotonate tautomerase Putative phosphofructokinaseRecalcitrant A HighA scoring Highscoring Amenable Highscoring Amenable Amenable Highscoring Amenable A A A ?A A AMR1 1 2 52X3F 2X7I 2X3L 2X4K 2JG5 2JG6 2JG2 [56] 2W82 [57] 2WJ9 2V1L [58]Sm Pt MRSA Se-SAD Zn MR MRSA MRSA MRSAZn-SAD MRSA MR Pt Pt MIRAS Sphingomonas paucimobilis Transposon Tn916 Escherichia coli Vibrio choleraeDNA-3-methyladenine glycosylase I 1 Serine palmitoyl transferase Antirestriction protein Antirestriction protein Hypothetical protein two three 4Recalcitrant ?Recalcitrant A Highscoring ARecalcitrant AThe Scottish Structural Proteomics Facility Table three continued Structures Phasing approach Origin Function/commentsRetrospective analysis of goal PDB code selection [reference] XtalPred ParCrys Cluster 2X7B 2X4I Sm-2X5G; Dm-2X5H 2X48 2X3G 2X5C 2X4J 2VXZ 2X3M 2X5R 2VH3 [54] 2VHS [59]Ard1 SIRV-ORF114 (CAG38848) SIRV-ORF131 (CAG38830) SIRV-ORF55 (CAG38821) SIRV-ORF119 (CAG38829) PSV-ORF131 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/21311040 PSV-ORF137 PSV-ORF165a PSV-ORF239 PSV-ORF126 Eukaryotes Ranasmurfin Cathepsin-L mutant MR Se-SADS.
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