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发布于:2019-12-3 19:07:27  访问:60 次 回复:0 篇
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Tients (11.8 ?6.0 /min vs 16.5 <a href="https://www.ncbi.nlm.nih.gov
Tients (11.8 ?6.0 /min vs 16.5 CS-0468 chemical information CS-0586 site PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/26438325 ?7.0 /min, purchase CS-0550 CS-0566 site 23952019" title=View Abstract(s)">PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/23952019 P < 0,05). Standardized resuscitation assessment laboratory measures and clinical evaluation tools were collected. The primary outcome in this prospectiveP274 Tissue oxygen saturation and the rate of tissue deoxygenation during stagnant ischemia in the medical emergency departmentM Me�nar, R Pare�nik, G Voga General Hospital Celje, Slovenia Critical Care 2007, 11(Suppl 2):P274 (doi: 10.1186/cc5434) Hypothesis Tissue oxygen saturation (StO2) and the rate of tissue deoxygenation during stagnant ischemia can early and reliably detect inadequate tissue oxygenation and assess prognosis in medical emergency room patients. Introduction Early recognition of patients with inadequate tissue oxygenation facilitates early diagnostic evaluation and treatment that was correlated with improved outcome. Near-infraredSAvailable online http://ccforum.com/supplements/11/Sstudy was the association between StO2 and the development of MOD within the first 24 hours based on a MOD score of 6 or greater. Clinicians were blinded from the StO2 values. Results Over a 14-month period, 78 patients were enrolled. Of the 78 patients, 26 (33.3 ) developed MOD within the first 24 hours. The MOD patients had mean (SD) initial StO2 values of 53.3 (?0.3), significantly lower than those of non-MOD patients (61.1 (?0.0); P = 0.002). The MOD patient mean shock index of 0.92 (?.28) was also significantly higher than those of non-MODS patients (0.73 (?.19); P = 0.0007).Tients (11.8 ?6.0 /min vs 16.5 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/26438325 ?7.0 /min, PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/23952019 P < 0,05). Age, lactate and rate of tissue deoxygenation but not StO2 were significant predictors of death (Table 1). There was weak but significant correlation between StO2 and age (P < 0.0001, r = ?.28), StO2 and lactate (P = 0.035, r = ?.12) and StO2 and systolic blood pressure (P < 0.0001, r = 0.26).Table 1 (abstract P274) Predictors of survival Predictor Age Lactate Deoxygenation rate Odds ratio 1.083 1.798 0.895 P value 0.004 <0.001 0.Conclusions StO2 and the rate of tissue deoxygenation during stagnant ischemia are promising additional variables, which can be measured rapidly and noninvasively in the emergency room setting. The rate of deoxygenation rather than StO2 may be helpful for early detection of patients with inadequate tissue perfusion and worse prognosis.P275 Near-infrared spectroscopy during resuscitation of trauma patients predicts development of multiple organ dysfunction: a prospective cohort studyB Nicks, K Hill, M Chang, W Bozeman Wake Forest University Health Sciences, Winston-Salem, NC, USA Critical Care 2007, 11(Suppl 2):P275 (doi: 10.1186/cc5435) Introduction Near-infrared spectroscopy (NIRS) noninvasively monitors muscle tissue oxygen saturation (StO2). It may provide a continuous measurement to identify occult hypoperfusion, guide resuscitation, and predict the development of multiple organ dysfunction (MOD) after severe trauma. We evaluated the correlation between initial StO2 and the development of MOD in multitrauma patients.
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